What is the treatment of hypokalemic periodic paralysis?
Acute attacks of weakness in patients with hypokalemic periodic paralysis can usually be treated with oral potassium preparations. Occasional patients, however, require intravenous (IV) potassium administration.
What are the treatments for periodic paralysis?
How is periodic paralysis treated?
- Close control of potassium intake through diet and supplements.
- IV (intravenous) potassium treatments, if symptoms are severe from hypokalemic PP.
- Control of carbohydrates in the diet.
- Control of thyroid function.
- Getting help from a nutritionist.
- Taking medicines such as acetazolamide.
How do you treat Hyperkalemic periodic paralysis?
Hyperkalemic periodic paralyses Fortunately, attacks are usually mild and rarely require treatment. Weakness promptly responds to high-carbohydrate foods. Beta-adrenergic stimulants, such as inhaled salbutamol, also improve the weakness (but are contraindicated in patients with cardiac arrhythmias).
How do you treat hypokalemia?
Hypokalemia is treated with oral or intravenous potassium. To prevent cardiac conduction disturbances, intravenous calcium is administered to patients with hyperkalemic electrocardiography changes.
Why acetazolamide is used in hypokalemic periodic paralysis?
A shift of extracellular to intracellular potassium has been suggested as a cause or concomitant of attacks in hypokalemic periodic paralysis. Since metabolic acidosis can diminish intracellular potassium,15 acetazolamide might reverse a tendency to an intracellular shift of potassium through production of acidosis.
What triggers hyperkalemic periodic paralysis?
Factors that can trigger attacks include rest after exercise, potassium-rich foods such as bananas and potatoes, stress, fatigue, alcohol, pregnancy, exposure to hot or cold temperatures, certain medications, and periods without food (fasting).
How long does it take to correct hypokalemia?
Typical patients with hypokalemia have required a mean of 5 days for return of their serum potassium levels to normal (12,13).
What are the emergency treatment options for Hypokalemic paralysis?
Emergency Treatment of the Hypokalemic Paralytic Attack 1 Monitoring. Measure serum K+ immediately and put electro-cardiographic monitoring in place. 2 Laboratory Studies. Resting membrane potential of muscle fiber in HypoKPP patients is always… 3 Treatment. If the patient presents with total paralysis of the extremities…
What is hypokalemic periodic paralysis?
Hypokalemic periodic paralysis is a rare channelopathy caused by the skeletal muscle ion channel mutations, commonly calcium channel and less commonly sodium channels.
Does treatment for hyperkalemic periodic paralysis improve attack rate and attack rate?
Twenty-four of 31 participants with hyperkalemic periodic paralysis completed both treatment phases: for the 16 participants who had attack rate data for both treatment phases, the mean improvement in attack rate (P = 0.006) and in severity-weighted attack rate (P = 0.02) on DCP relative to placebo were significant.
What is periodic paralysis (pp)?
Periodic paralysis (PP) is a rare neuromuscular disorder related to a defect in muscle ion channels, characterized by episodes of painless muscle weakness, which may be precipitated by heavy exercise, fasting, or high-carbohydrate meals.