Can amiodarone cause anemia?

Can amiodarone cause anemia?

INTRODUCTION: Amiodarone is associated with several adverse effects, including hematologic side effects such as pancytopenia, hemolytic anemia and aplastic anemia. Very few cases of amiodarone-induced bone marrow granulomas have been reported.

Does amiodarone affect hemoglobin?

The patient deteriorated rapidly despite discontinuation of the amiodarone therapy. Hemoglobin and white cell count decreased gradually and platelet count remained extremely low resulting in profound pancytopenia.

What side effects may be expected during amiodarone infusion?

Common side effects of Cordarone IV (amiodarone hydrochloride) include:

  • low blood pressure (hypotension),
  • slow heart rate,
  • cardiac arrest,
  • nausea,
  • fever,
  • congestive heart failure,
  • abnormal heart rhythm,
  • cardiogenic shock, and.

What is the most common side effect following administration of intravenous amiodarone?

Hypotension. Hypotension is the most common adverse effect seen with intravenous amiodarone. In clinical trials, treatment-emergent, drug-related hypotension was reported as an adverse effect in 288 (16%) of 1836 patients treated with intravenous amiodarone.

Does amiodarone cause low platelets?

Amiodarone has been implicated as a cause of thrombocytopenia but the responsible mechanism is unknown. We performed studies in three patients to characterize the pathogenesis of this complication. No amiodarone-dependent, platelet-reactive antibodies were identified using conventional serological techniques.

What are two adverse effects of amiodarone?


  • Cough.
  • dizziness, lightheadedness, or fainting.
  • fever (slight)
  • numbness or tingling in the fingers or toes.
  • painful breathing.
  • sensitivity of the skin to sunlight.
  • trembling or shaking of the hands.
  • trouble with walking.

What is the most common drug induced thrombocytopenia in hospitalized patients?

Heparin, a blood thinner, is the most common cause of drug-induced immune thrombocytopenia. If a medicine prevents your bone marrow from making enough platelets, the condition is called drug-induced nonimmune thrombocytopenia.

What should be avoided when taking amiodarone?

You should avoid consuming grapefruits and grapefruit juice while taking amiodarone. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Grapefruit can raise the levels of amiodarone in your body and lead to dangerous side effects.

Are amiodarone side effects reversible?

The results of the article in this issue of the journal appear consistent with those in a practical guide published in 2007, with incidence of adverse effects of 15% during first year of amiodarone use increasing to up to 50% during long-term use [2]; there was higher frequency of adverse effects in patients on …