Does aspartame cause permanent damage?
Long-term aspartame administration resulted in many degenerative changes affecting mainly the myelin sheath, in the form of focal and extensive demyelination; disruption and splitting of myelin lamellae with loss of compact lamellar structure; and excessive enfolding with irregular thickening of myelin sheaths.
What is the most dangerous digestive product of aspartame?
As an ingredient in many food products, aspartame, the metabolite of which is phenylalanine, is particularly harmful to people with phenylketonuria. During digestion, aspartame releases 50% of its mass in the form of phenylalanine, which leads to an increase in its level in the blood.
What are the side effects of aspartame?
However, research shows that the side effects of aspartame may include increased risk of weight gain (rather than weight loss) and impaired glucose tolerance in type 2 diabetics. 11
Does aspartame cause cancer in mice?
Soffritti M et al. “Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice.” Am J Ind Med. 2010 Dec; 53 (12):1197-206. PMID: 20886530. (abstract / article)
How reliable is the EFSA’s 2013 safety assessment of aspartame?
In a July 2019 paper in the Archives of Public Health, researchers at the University of Sussex provided a detailed analysis of the EFSA’s 2013 safety assessment of aspartame and found that the panel discounted as unreliable every one of 73 studies that indicated harm, and used far more lax criteria to accept as reliable 84% of studies that found…
What is the prognosis of aspartame toxicity in rats?
Soffritti M, Belpoggi F, Tibaldi E, Esposti DD, Lauriola M. “Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats.” Environ Health Perspect. 2007 Sep;115 (9):1293-7. PMID: 17805418. (article)