What is the active ingredient in NyQuil?

What is the active ingredient in NyQuil?

There are three active ingredients in NyQuil: acetaminophen, dextromethorphan (DXM), and doxylamine. Acetaminophen reduces fever and alleviates minor pain, dextromethorphan suppresses coughing, and doxylamine is an antihistamine (anti-allergy medication) which relieves congestion, sneezing, and sore threat.

Can I take Zyrtec and NyQuil at the same time?

Using cetirizine together with doxylamine may increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

Is Zyrtec the same as NyQuil?

Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) Relieves congestion and allergy symptoms. Zyrtec D (Cetirizine / Pseudoephedrine) relieves allergies and congestion without causing daytime sleepiness. It can keep you up at night if you take it too close to bedtime.

Does Zyrtec have diphenhydramine in it?

Zyrtec and Benadryl are brand names for cetirizine and diphenhydramine, respectively. Zyrtec and Benadryl are both antihistamines that block histamine receptors and provide allergy relief.

What ingredients are in Zyrtec?

Active Ingredients

Active ingredient (in each extended release tablet) Purpose
Cetirizine HCl 5 mg Antihistamine
Pseudoephedrine HCl 120 mg mg Nasal decongestant

What ingredients are in Nyquil severe cold and flu?


  • Acetaminophen 650 mg (in each 30 mL)
  • Dextromethorphan HBr 20 mg (in each 30 mL)
  • Doxylamine Succinate 12.5 mg (in each 30 mL)
  • Phenylephrine HCl 10 mg (in each 30 mL)

Is Diphenhydramine the same as cetirizine?

RATIONALE: Cetirizine is a second generation antihistamine with a longer duration of action and less sedation than diphenhydramine. While diphenhydramine is traditionally used in the treatment of food allergic reactions, its sedating properties can interfere with the assessment of patients.