What is the difference between satellite DNA minisatellite DNA and microsatellite DNA?
What is the difference between satellite DNA minisatellite DNA and microsatellite DNA?
The main difference between microsatellite and minisatellite is that the repeating unit of a microsatellite consists of 2-6 base pairs while the repeating unit of a minisatellite consists of 10-100 base pairs.
Do satellite DNA shows polymorphism?
shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children.
What is microsatellite polymorphism?
Microsatellites are short tandem repeats of 1- to 6-nucleotide motifs; they are often highly variable and polymorphic within the genome, which raises the question of whether they may be used as molecular markers for the precise differentiation of HSV-1 strains.
What is minisatellite DNA?
A minisatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 10 to 60 base pairs) are typically repeated 5–50 times. Minisatellites are notable for their high mutation rate and high diversity in the population, and they occur at more than 1000 locations in the human genome.
What is the difference between STR and VNTR?
VNTR consists of comparatively a long repeating units of nucleotides (10-60 base pairs). STR consists of short repeating units of nucleotides (2-6 bp). The main difference between VNTR and STR is the length of the repeating units of each type of tandem repeats.
What is a polymorphism in DNA?
Polymorphism, as related to genomics, refers to the presence of two or more variant forms of a specific DNA sequence that can occur among different individuals or populations. The most common type of polymorphism involves variation at a single nucleotide (also called a single-nucleotide polymorphism, or SNP).
What is true about satellite DNA?
Satellite DNA (satDNA) is the highly repetitive DNA consisting of short sequences repeated a large number of times. It carries a variable AT-rich repeat unit that often forms arrays up to 100 Mb. The monomer length of satDNA sequences ranges from 150 to 400 bp in the majority of plants and animals.
Why are microsatellites used in DNA profiling?
Microsatellites in non-coding regions may not have any specific function, and therefore might not be selected against; this allows them to accumulate mutations unhindered over the generations and gives rise to variability that can be used for DNA fingerprinting and identification purposes.
What are minisatellite used for?
Minisatellites are the most highly variable sequence element in the human genome and the variable number of tandem repeats (VNTR) is used for DNA fingerprinting analysis in forensic science.
What is satellite DNA in a genome?
Satellite DNA is a fraction of the eukaryotic genome consisting of highly repetitive noncoding short sequences organized in tandem arrays within the heterochromatin. Satellite DNA sequences are the main component of heterochromatic genome regions, which remain condensed throughout the cell cycle.