Which drugs are calcium channel blockers?

Which drugs are calcium channel blockers?

Examples of calcium channel blockers include:

  • Amlodipine (Norvasc)
  • Diltiazem (Cardizem, Tiazac, others)
  • Felodipine.
  • Isradipine.
  • Nicardipine.
  • Nifedipine (Procardia)
  • Nisoldipine (Sular)
  • Verapamil (Calan SR, Verelan)

How is nifedipine converted to amlodipine?

implementing the switch from nifedipine GITS to amlodipine:

  1. patients taking nifedipine 30 mg or 60 mg daily should be.
  2. switched to amlodipine 5 mg daily, and those taking nifedip-
  3. ine 90 mg or 120 mg daily should be switched to amlodipine.
  4. 10 mg daily These recommendations were not mandatory,

What is the pharmacokinetics of the calcium channel blocker?

The pharmacokinetics of CCBs are as follows: Amlodipine (Norvasc): Peak plasma level, 6-9 hours; half-life, 30-50 hours. Bepridil (Vascor): Peak plasma level, 2-3 hours; half-life, 24 hours. Diltiazem immediate release (IR) (Cardizem): Peak plasma level, 2-4 hours; half-life, 3.5-6 hours.

What is the difference between amlodipine and nifedipine?

Abstract. Nifedipine is an effective compound for the treatment of hypertension. However, even as a tablet formulation it is relatively short acting requiring two or three times daily administration. Amlodipine is a long-acting calcium antagonist and effectively lowers BP in patients with essential hypertension.

What is equivalent to amlodipine?

Nifedipine, lisinopril, losartan, and carvedilol are some amlodipine alternatives. Get the full list here. Amlodipine is a generic medication prescribed to treat high blood pressure. In addition to treating high blood pressure, amlodipine is approved to treat angina and other problems with coronary artery disease.

Which is better diltiazem or amlodipine?

Although both agents were well tolerated and reduced blood pressures consistently over the 10-week test period, amlodipine was more effective than diltiazem in reducing systolic and diastolic blood pressures to the target pressures of < 140 mm Hg systolic and < 90 mm Hg diastolic over a range of doses widely used in …

What is the pharmacokinetics of amlodipine?

Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of ionisation. Following oral administration, bioavailability is 60 to 65% and plasma concentrations rise gradually to peak 6 to 8h after administration.

How are calcium channel blockers distributed?

Distribution: Calcium channel antagonists are highly protein-bound, and many have high volumes of distribution. Metabolism: In repeated doses, or overdose, the hepatic enzymes responsible for metabolism become saturated and reduce first-pass effects, which therefore increases absorption of the active drug.